Insulin Sensitivity Management: Berberine
AMPK and its agonist, berberine, can combat some underlying events of neurodegeneration
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Biochemistry
Hmm.. Thor has an Upregulated mTOR
Curcumin, a compound found in turmeric, has anti-aging effects by the inhibition of mTORC1 activity
Mitochondria: from Energy to Brown Fat
Amino acids yield lower amounts of ATP than glucose as they enter the energy production cycle later in the process
Digestion: Omega, Gut, Fat & Bile
The presence of high levels of fat in the diet can inhibit the absorption of carbohydrates, while high levels of fiber (non-digestible carbs) can interfere with the absorption of fat
Nitrogen to Ammonia to Urea: Toxic Alert
Eating a low protein diet can help to reduce the amount of excess nitrogen in the body and minimize the burden on the urea cycle
Fasting – Recycle – Autophagy
There are two main pathways involved in nutrient availability that inhibit or suppress autophagy: cAMP-dependent protein kinase A (PKA) and mTOR (mechanistic target of rapamycin)
Methylation: Beyond Creatine & DNA
COMT is responsible for the methylation of catecholamines, such as dopamine, norepinephrine, and epinephrine
Selenium & Glutathione Conjugation
GPXs are selenoproteins, for which the availability of selenium is of key importance
Cortisol & Drugs Genetics: Acetylation
By acetylation, hydralazines are turned into hydrazides, which can then be excreted easier
What do Aspirin, BPA & NSAIDs have in common? Glucuronidation!
Mycotoxins are substances made by fungi that are present in many foods, such as cereals, nuts, and spices