Antioxidants ARE Nrf2. Wait, What?
Nrf2 is the master antioxidant regulator of the body and you need it to be top notch, for you to be protected against cellular oxidation
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Biochemistry
Genetics of Electromagnetic Fields
EMF exposure may be also linked to an increase in interleukin 6 (IL-6), a pro-inflammatory cytokine
NOX Enzyme: NADPH Steal and the Holmes Cycle
The NADPH steal results in less available NADPH to support Phase 1 Detox, produce Nitric Oxide and recycle critical antioxidants, such as Glutathione
CBS News: Sulfites and Inflammation
SUOX is responsible for breaking down sulfites into sulfates, which are then eliminated from the body through urine
Iron to Heme to Hemoglobin Essentials
When oxygen is inhaled, it binds to the iron atom in the heme, allowing hemoglobin to transport it through the bloodstream to the tissues that need it
Oxalobacter: Gut’s Best Friend Forever
One of the key ways in which oxalates can contribute to inflammation in the body is through the activation of the NLRP-3 inflammasome
Allergy Stories: Are you Anti Histamine?
Histamine causes a number of physiological changes in the body, such as an increase in heart rate, blood vessel dilation, and mucus production
Glutamate & Excitotoxicity
Curcumin lowers glutamate levels by preserving glutamate transporter GLT-1 expression and function, leading to an attenuation of excitotoxicity
Fenton: linking Iron and Inflammation
Hydrogen peroxide (H2O2) can be hijacked by the Fenton reaction to produce highly inflammatory hydroxyl radicals (OH-)
Inflammation: Nitric Oxide Synthase
Nitric oxide synthase (NOS) is an enzyme that helps the body manage inflammation by producing nitric oxide (NO)