Heat Shock Proteins
HSPs have been demonstrated to defend against a variety of diseases, including cancer, neurological disorders, and cardiovascular disease
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Antioxidants
Selenium & Glutathione Conjugation
GPXs are selenoproteins, for which the availability of selenium is of key importance
PON: Cholesterol Meets Detox
Pomegranate polyphenols can enhance PON2 expression, whereas consuming yerba mate can enhance all PON enzymes’ activity
FOXO: the Insulin Controller
FOXO3 activation extends lifespan in animal models, and has been suggested to be a potential target for interventions to promote healthy aging in humans
Sirtuins and Healthy Aging
While SIRT7 has been implicated in the control of gene expression, SIRT6 has been implicated in the repair of DNA damage
Catalase: Glutathione’s Sancho Panza
One catalase enzyme can change 40 million molecules of hydrogen peroxide into water and oxygen per second
SuperOxide Dismutase: The AOX Hero
Cantaloupe juice concentrate and apple polyphenols have been shown to increase SOD levels in several human trials
NAD(H) & NADP(H), Your AntiOx Best Friends
Sirtuins have been shown to have a variety of effects on aging and longevity and NAD+ is involved in the regulation of gene expression through the action of these enzymes
Antioxidants ARE Nrf2. Wait, What?
Nrf2 is the master antioxidant regulator of the body and you need it to be top notch, for you to be protected against cellular oxidation
Glutathione – the master antioxidant
Glutathione conjugation is one of the 6 phase 2 detox pathways of the body, responsible for approximately 60% of toxin processing